Ingredients: Apium graveolens, Trachyspermum copticum, Acacia Arabica, Honey, Saccharam officinarum

 Active Ingredients: Limonene, Quercetin ,glycosides,furanocoumarins ,flavones ,trace elements (Na, K, Ca, Fe), steroids,jwain oil constituents (camphene, pinene, yrcene, limonene, terpinene, terpinen- 4-ol, thymol and carvacrol,

Indications: To strengthen the stomach and anti-flatulence

Dosage and administration: Take 1-2 tablets twice a day after meals

Side effects: Consumption of the recommended amounts is not associated with any side effects.

Recommended tips: Do not take for more than 45 consecutive days.

Contraindications and precautions: Pregnancy and lactation and those who suffer from constipation

Pharmacological effects and mechanism of action MOA: This product is traditionally used as an important compound for the treatment of flatulence, atonic dyspepsia, diarrhea, abdominal tumors, abdominal pain, anorexia, milk enhancer, asthma and amenorrhea. In terms of medicine, it has various medicinal activities such as antifungal, antioxidant, antimicrobial, analgesic, cytotoxic, blood fat reduction, antihypertensive, antispasmodic, bronchodilator effects, antistone crusher, antiflatulence, diuretic, abortion. It is an antitussive cream. Ajwain with the right heat helps manage digestive problems by strengthening the digestive fire. It also helps in easy digestion of food and relieves stomach bloating. Ajwain also improves digestion and helps remove toxins from the body to relieve problems such as constipation, acidity and gas. Along with a better digestive system, ajwain can help prevent bloating, reduce acidity, and reduce stomach pain and other discomforts. improve liver blood flow and ultimately help reduce ascites and blood pressure

This product is able to remove all the gases, which are called wind (flatus) and from the three sources of swallowing air (aerophagia), gases resulting from the activity of bacteria in the intestine and gases released from the blood into the digestive system that enter the body. Inhibits and prevents crampy pains associated with the accumulation of gases in the upper or lower part of the digestive system. It is said that the produced essential oils, in addition to relaxing the lower esophageal sphincter as well as rapid absorption and removal of gastrointestinal gases, also have anti-flatulent and stomach strengthening properties due to the presence of limonene and other suitable essential oils. are. Antiflatulent activities and reduction of malignant activities in gastric and intestinal volume have been shown to be associated with relaxation of the esophageal sphincter, possibly releasing gastric gas. Antimicrobial activity helps reduce intestinal gas. Terpenoids with flavonoids are beneficial in digestive function. Studies have shown that quercetin inhibits gastric acid secretion and lipid peroxidation of gastric cells and thus acts as a protective agent in the stomach. It also inhibits the activity of Helicobacter pylori. Anti-ulcer activity of quercetin due to its free radical scavenging property or increasing the production of gastric mucus. Therefore, Opium Gorolens (Karafs), which is used as an anti-congestive, anti-spasmodic, carminative, diuretic, laxative, sedative. The seeds of Trachyspermum copticum contain brown oil known as aviin oil. The main component of this oil is thymol, which is used in the treatment of stomach and intestinal diseases, lack of appetite and bronchial problems. It is an important remedy for flatulence, atonic dyspepsia and diarrhea.

Pharmacological effect of this product from the perspective of traditional medicine:

From the point of view of the basics of traditional medicine, whenever foreign moisture enters the

 stomach from the food essence and the stomach heat is not overcome, the food turns into steam

 and belly wind occurs. It should be noted that if the food has windy but the heat prevails. There

will be no wind, so people with a cold temper, especially when their stomachs are cold, Flatulence

is produced. The formula of Healthy Flatulence with 2 G Grade and 1.5 Dry Grade Nature, with its

special properties, digestion and windbreak, is able to dilute and dry the accumulated air by

 heating and drying it, and thus expel it to the outside

 References: 1-PMC/Overviews of biological importance of quercetin: A bioactive flavonoid/2016

2-Pmc/An Updated Phytopharmacological Review on Medicinal Plant of Arab Region:

3-Apium graveolens Linn/2017

4-sciencedirect / Limonene

5-Pmc/Trachyspermum ammi/2017

6-pdr books/page423

7-https://fa.wikipedia.org/wiki

                8-ftn.srbiau.ac.ir/article_1272_7e79782ad1c6370466678e550dac2949.pdf

استاد یار گروه شیمی آبرومندآذر.پرویز و استادیاردانشکده علوم مهندسی شریفان.انوشه و مربی مجتمع آزمایشگاهی لاریجانی.کامبیز