Ingredients:Malva sylvestris, Honey ,Starch
Active Ingredients:polysaccharides, anthocyanins,coumarins, tannins, flavones, flavonols, anthocyanidines, leuco-anthocyanidines, mucilagen and essential oil
Indications:Scabies (itchy skin disease, moderate to severe eczema) with symptoms of allergies such as urticaria, pruritus, beneficial skin diseases and in eczema in dry and wet forms.
Dosage and administration:Every 12 hours, a tablet is poured into a glass of lukewarm water and swallowed after glazing.
Side effects:For people with a cold temper, it is necessary to use its remedy, which is mentioned in the recommended points.
Recommended tips:In acute and severe cases of the disease to achieve the desired effect, the dose can be increased every 8 hours to 2 tablets to achieve the desired effect.
Contraindications and precautions:Hypothyroidism ، psoriasis, pregnancy
Pharmacological effects and mechanism of action MOA: What should be kept in mind in terms of the scientific approach to the treatment of allergic diseases is the precise understanding of the difference in processes: allergy and sensitivity, eczema and inflammation. The difference between allergy and inflammation is that inflammation is the body's response to tissue damage and is always accompanied by repair, but allergy is an exaggerated response of the immune system to the contact of a foreigner that has been inhaled, touched, or swallowed. But the difference between allergy and eczema is that allergy is a general term that refers to all types of skin and non-skin sensitivities, such as rhinitis, but eczema is a skin allergy that occurs as a result of direct or indirect contact with an external agent, which is called dermatitis. It is also said that the difference between eczema and skin allergy is that in allergy, hives are caused by an allergic reaction in the form of red raised areas with a warm surface, but eczema is dry, cracked, pimpled skin with papules (a small bump on the surface of the skin or a vesicle (fluid-filled sac). (or erythema (redness of the skin surface without bumps) in the form of a piece that causes dilation of the capillaries) and sometimes it is accompanied by hyperkeratosis (abnormal thickening of the outer layer of the skin) . There are many fractions isolated from Malva sylvestris, but its main BIO Active compound for controlling inflammation and treating allergies and eczema includes: anthocyanins, coumarins, flavonoids, and of course tannins, mucilages and essential oils are also among other therapeutic phytochemicals of the plant. The flavonoid quercetin inhibits the enzyme lipase A2, which is a very important factor in inflammatory conditions, and is actually an enzyme that converts the phospholipids of the cell membrane into arachidonic acid, which is converted into PROG by the enzyme cyclooxygenase, and by inhibiting it in the initial stage of this The process prevents the production of the main progressive factor of inflammation (remembering that the regulation of the inflammation process as a defensive reaction of the body or its prevention is the responsibility of the intelligent phenomenon inside the body, or Cellular redox homeostasis, which recognizes what mechanism even the internal factors are responsible for). And this is the truth that we see that some important substances in the body have opposite functions, such as cytokines and pseudostaglandins (another group of coumarins is called escopultin, which inhibits the signal cascade of a type of cytokines that is responsible for the production of mast cells. They are responsible for leukocytes and contain histamine and heparin granules, and coumarin inhibits these signals. Anthocyanin called malvidin 3-glucoside, which inhibits a type of cytokine inflammatory mediators that causes absorption and activation and helps the phagocytic process, thus ending the immune response.
Pharmacological effect of this product from the perspective of traditional medicine: From the point of view of traditional medicine, this product, primarily with its solvent and tonic properties, eliminates rotten sputum. And prevent the effects of waste products on the limbs, and then with the help of relaxing properties and bathing also cause softening of the limbs. It also dilutes and removes rotten impurities and curbs chronic coughs
References: 1-ResearchGate/ Malva Sylvestris in the treatment of hand eczema/2010 2-PubMed/Pre-clinical efficacy assessment of Malva sylvestris on chronic skin inflammation /2017 3-PubMed/Pre-clinical anti-inflammatory aspects of a cuisine and medicinal millennial herb: Malva sylvestris L./2013
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