Eye Contour Cream

Ingredients :   Deionized water, glycerin, glycerol monostearate, liquid paraffin, coriander oil extract, beeswax, cetyl alcohol, essential oil, methyl paraben, butylated hydroxytoluene.

Active Ingredients: Alkaloids. Flavonoids .Tannins.  Phenols.  Saponin. Cardiac glycoside. Steroids. linalool(57.57%); geranyl acetate (15.9%); -caryophyllene (3.26%), camphor (3.02%), and p-cymene (2.5%)flavonoids include quercetin, kaempferol, apigenin and acacetin and the phenolic acids identified are vanillic acid, ferulic acid  

 Indications: reducing wrinkles around the eyes, helping to remove dark circles around the eyes, helping to reduce puffiness under the eyesIt is recommended to be used for warm or warm skinDosage and administration: First, clean and dry your skin with a mild cleanser, then spread a small amount of cream around the eyes with a gentle circular motion until it is absorbed. Continue doing this regularly to get better results.

Side effects: So far, no specific side effects have been reported

Recommended tips: It is recommended to test some cream on a part of the neck or behind the ear 24 hours before use and use it if you are sure that there is no allergy.

Contraindications and precautions: Not recommended for severe allergies and psoriasis.

Pharmacological effectsand mechanism of action MOA: In recent years, the increasing demand for pharmaceutical and cosmetic products containing natural   active ingredients has drawn researchers' attention  to  essential oils (EOs). Plants  from the  Apiaceae  family  are  apotential source of drugs  such as  essential oils, t erpenoids,  triterpenoid  saponins,  flavonoids,  coumarins,  polyacetylenes  and  steroids.  The  essential  oils  obtained  from  the  fruits  of  this  family  have   anti-tumor, anti-wound,  antimicrobial,  antioxidant,  anti-inflammatory,  anti-spasm,  antiseptic  and  anti-wrinkle effects.

The most  common  piaceous  members  that  are  traditionally  used  are  fennel,  anise,  cumin and coriander. The essential oil s howed  a  very  high level of oxygenated monoterpenes, of which linalool (81.29%) was the most abundant compound. Surprisingly, coriander oil cream and lipid  nanoparticles  formulation  containing coriander essential oil (CEOLNs) reduced UV-induced skin aging in vivo, which  was significantly reduced by MDA, COX-2, PGE-2, MMP-1, JNK, and AP- were revealed. In

 addition, these drug forms significantly increased the collagen content of the  skin compared  to  the  UV-damaged  group. Also,  coriander  essential  oil   significantly increased the protein expression level of TGFβ, TGFβII and SMAD3 compared to the group damaged by ultraviolet rays. As  a  result, the  medicinal  forms  of  coriander oil  have anti-wrinkle activities that can play a beneficial role in correcting external aging..

 

References:

Scientific Reports/Coriander (Coriandrum sativum L.) essential oil and oil-loaded nano-formulations as an anti-aging potentiality via TGFβ/SMAD pathway/2022 Article number: 6578 (2022)

 

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